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ورود به زیرشاخهPURPOSE: Perinatal mood disorders are associated with adverse maternal and neonatal outcomes and affect 15%-20% of pregnant people. Guidelines recommend SSRIs when non-pharmacological therapies are ineffective, yet antenatal depression remains undertreated. This study aimed to assess the attitudes, knowledge, and practices of general practitioners (GPs) and midwives on SSRI use in pregnancy. METHODS: A knowledge, attitudes, and practice survey was developed in QualtricsXM and distributed to New Zealand-registered GPs and midwives between May 2023 and October 2024 using convenience sampling. RESULTS: Responses from 119 GPs and 62 midwives were analyzed. Discomfort managing antenatal depression was reported by 11% of GPs and 36% of midwives. Knowledge of SSRI risks in pregnancy varied among respondents. Average concern regarding the use of SSRIs in pregnancy and the risk of adverse outcomes was low, but there was considerable variation. In the case vignette, recommended actions differed: 53% advised maintaining treatment, 13% suggested dose reduction, and 24% recommended switching antidepressants. Patient counseling was limited, and appropriate written patient information was rarely provided. CONCLUSIONS: This study highlights variability in knowledge, attitudes, and practices among GP's and midwives regarding SSRIs during pregnancy. Further training, improved access to patient information, and decision aids could enhance patient-centered care and ensure pregnant people receive balanced, evidence-based guidance on SSRI use.
Disaster response in neonatal intensive care units is particularly complex because care continuity depends on coordinated teamwork, stable infrastructure, and technology-dependent support for highly vulnerable infants. However, qualitative evidence on how nurses experience disaster response in these settings remains limited, especially in the context of the 2023 Türkiye-Syria earthquakes. This study explored how nurses working in neonatal intensive care units experienced disaster response during the earthquakes. Data were collected through semistructured in-depth interviews with 21 nurses and analyzed using descriptive phenomenological analysis. Participants described disaster response not only as a clinical emergency but also as a disruption of the systems supporting coordination, safe neonatal care, and practical preparedness. They reported breakdowns in communication and role clarity, fragility in care when electricity, oxygen delivery, monitoring systems, evacuation planning, and essential supplies became unstable, and a clear gap between general disaster education and unit-specific readiness. Overall, the findings highlight the need for neonatal intensive care-specific disaster preparedness.
AIM: To evaluate the effectiveness of educational programs on disaster preparedness and management for emergency nurses and nursing students, focusing on teaching methods that enhance readiness and competence. BACKGROUND: The increasing frequency and severity of disasters require healthcare systems to be adequately prepared. Nurses, often on the frontline, must receive structured and effective training to respond to critical events with competence and resilience. METHODS: A Rapid Evidence Assessment was conducted to explore and synthesize the available literature on educational interventions in disaster preparedness. Studies were identified through structured searches in international databases and were selected and evaluated using the PRISMA 2020 checklist. The quality of included studies was appraised using the CASP tool. RESULTS: Thirty-six studies met the inclusion criteria. Educational programs incorporating realistic simulations, virtual technologies, and interprofessional exercises were most effective in improving technical skills, confidence, and crisis management. Programs varied in format and intensity but shared common elements such as experiential learning and integration of psychological preparedness. DISCUSSION: Educational interventions must balance theory with practice and adapt to diverse cultural and contextual needs. Simulations and technology-enhanced learning emerge as critical strategies to reinforce emergency competencies. CONCLUSION: Educational programs in disaster preparedness positively influence nurses' readiness, skills, and confidence. Integrating these interventions into nursing education is essential to prepare a responsive and resilient workforce. IMPLICATIONS FOR NURSING: Ongoing and structured education strengthens nurses' ability to respond effectively during disasters, promoting professional growth and emotional resilience. IMPLICATIONS FOR HEALTH POLICY: Policies should support the mandatory inclusion of disaster preparedness training in nursing curricula and continuing education. National frameworks must prioritize standardized educational models to ensure healthcare system resilience and nurse preparedness worldwide.
BACKGROUND: Genomics is reshaping healthcare and is increasingly recognized as essential to nursing. Although international organizations call for aligned genomic competencies, integration in undergraduate education remains limited. Curriculum-mapping studies show what is taught, but little is known about how educators interpret genomic relevance or navigate institutional constraints. AIM: To explore how nursing educators in Portuguese higher education institutions understand, value, and operationalize genomics within nursing education programs. METHODOLOGY: A qualitative, exploratory study grounded in interpretivist and reflexive epistemology was conducted through online focus groups with ten nursing educators. Data were generated through dialogic discussions and analyzed using reflexive thematic analysis. RESULTS: Three themes captured shared meanings. Educators viewed genomics as aligned with holistic and person-centered nursing. However, its curricular presence was described as fragmented, implicit, and predominantly taught through biomedical lenses. Structural constraints, such as curriculum saturation, regulatory rigidity, uneven faculty expertise, and reduced contact hours, were perceived as barriers to systematic integration. Participants also constructed feasible pathways to achieve integration, including transversal embedding, case-based pedagogies, flexible initiatives, and interprofessional collaboration. DISCUSSION: Educators' interpretations illustrate how global recommendations are adapted within local realities. They also highlight pragmatic strategies that can support incremental and context-sensitive integration of genomics into nursing education. CONCLUSION: Purposeful integration requires coordinated action across pedagogical design, faculty development, and system-level structures. IMPLICATIONS FOR NURSING: Strengthening faculty preparation and embedding genomic concepts across curricula can enhance genomic literacy. IMPLICATIONS FOR HEALTH POLICY: Aligning educational standards and regulatory frameworks with genomic competencies is key to preparing a genomics-ready nursing workforce.
AIM: To map the available evidence on the assessment of migrant nurse and midwife workplace integration in global healthcare settings. BACKGROUND: Globally, migrant nurses and midwives are important resources in mitigating workforce shortages. Existing evidence focuses on the orientation stages of migrant nurse and midwife transition into the healthcare setting rather than their long-term workplace integration. DESIGN/METHODS: The nine databases searched were CINAHL, Medline, Web of Science, Embase, PsycINFO, ASSIA, SicELO, Maternity & Infant Care and Global Index Medicus. An initial search was performed in December 2021 and updated in December 2025. RESULTS: A total of 91 articles were included, comprising qualitative (n = 48), quantitative (n = 13), mixed-methods (n = 6), others (n = 23) and one book chapter. Multiple definitions of workplace integration were found, and 23 tools were identified. CONCLUSIONS: Workplace integration, a multidimensional, time-dependent process, requires collaboration among stakeholders. A standard definition will help to clarify their responsibilities. Key factors ensuring successful integration include promoting effective communication, supporting knowledge advancement, facilitating career development and skill utilisation. The development of standardised interventions with flexibility for local adaptation will support successful workplace integration. IMPLICATIONS FOR NURSING/HEALTH POLICY: Findings highlight the need for policy developers to support migrant nurses and midwives with interventions focused on linguistic challenges, cultural competence and differing care models, that are key to successful integration. Future research must include host stakeholders' perspectives to fully understand the dynamics of workplace integration.
INTRODUCTION: HOPtimise is an organisational innovation in paediatric oncology in the province of Québec (Canada) destined to improve and reinforce best nursing practices through digital training using a serious game and create dashboards focused on indicators sensitive to the quality of care. This complex intervention is led by a quality improvement committee, a joint committee of user partners (former patients and family members) and healthcare providers. The present study aims to demonstrate how innovation and training are co-created with multiple stakeholders. The involvement of patients and their families is at the core of the innovation's design. The aim of this study was to create and elaborate on the components of the logic model of the innovation in order to make it easily understandable for any stakeholder, to set the central roles and activities of the innovative process and to be able to verify the progress of the elaboration and the implementation of the innovation afterwards. The study also intended to generate guidance for future complex interventions in nursing practice improvement. DESIGN: This study has a qualitative, descriptive and participatory design with a mixed data collection destined to create the logic model of the innovation. The qualitative methods used are organised through a three-step timeline: the elaboration of the logic model, the verification phase and validation. Data collection methods involved two focus groups, each one at a different phase of the process (n = 9 and n = 6), semi-structured interviews (n = 4) and verification checklists (n = 9) conducted from June 2022 to June 2024. Data collection guides are based on the Porteus (2009) method for the elaboration of a logic model. Through the process, n = 15 participants took part in at least one data collection (either focus group or interviews). RESULTS: With a 2-year and n = 15 multistakeholder study, the team obtained a logic model of organisational innovation. The HOPtimise logic model is a necessary tool to communicate with all stakeholders from various backgrounds. The study shows that the logic model was clear enough to all the participants (n = 15). As a result, this logic model is a strong base to stabilise the roles and activities of those stakeholders in the elaboration and implementation of the innovation. Indeed, it allowed the building of a stable quality improvement committee. Finally, the logic model became a baseline for the process of identifying barriers and implementation strategies. CONCLUSIONS: The HOPtimise logic model is representative of the complexity of the organisational innovation and the organisational challenges that the project will encounter, and is a necessary tool for evaluation of its implementation in terms of its co-constructive nature. PATIENT AND PUBLIC CONTRIBUTION: This study is a co-creation and is family-centred. It involved the engagement and participation of user partners and organisational members. The research team interacted with them during the three steps of the elaboration of the logic model. They provided opinion and expertise on the content of the innovation, its components, the activities needed to reach the outcomes and implementation strategies.
BACKGROUND: The 2019 medication regimen complexity-intensive care unit (MRC-ICU) score is associated with patient outcomes, ICU complications, and critical care pharmacist workload. This score was developed using heuristic component selection and validated in a single-center cohort of 130 ICU patients. We sought to apply data-driven reweighting methodology in a large, multicenter cohort of ICU adults to improve the predictive capabilities of MRC-ICU. METHODS: This was a retrospective, observational cohort study of adults admitted to an ICU between 2015 and 2023 at two academic health systems. Machine learning-based methods, including Principal Component Analysis and Random Forest, were used to create an updated MRC-ICU score optimized to predict three outcomes: hospital mortality, ICU fluid overload (FO) occurrence, and invasive mechanical ventilation (IMV) use. MRC-ICU 2.1 used average mortality, FO, and IMV use; MRC-ICU 2.2 used average mortality and FO and adjusted for prolonged IMV use. Data from one center were used for training and testing, and data from the other for validation. The predictive abilities of MRC-ICU 2.1 and 2.2 for each outcome were compared to MRC-ICU 1.0 and to severity of illness scores (i.e., Acute Physiology and Chronic Health Evaluation [APACHE] II and Sequential Organ Failure Assessment [SOFA]). RESULTS: A total of 19,117 patients across training, testing, and validation datasets were included. MRC-ICU 2.0 scores outperformed MRC-ICU 1.0 for predicting most outcomes, with improvements in Area Under the Receiver Operating Characteristic (AUROC) ranging from +0.03 to +0.08 across datasets. MRC-ICU 2.1 and 2.2 did not consistently outperform APACHE II and SOFA in predicting mortality. The addition of MRC-ICU 2.0 scores to models including APACHE II or SOFA resulted in statistically significant improvements in discrimination in several settings (DeLong p < 0.05), with AUROC increases generally ranging from approximately +0.01 to +0.13 depending on outcome and dataset. CONCLUSIONS: The updated MRC-ICU 2.0 score (MRC-ICU 2.1 and 2.2) demonstrated consistently improved discrimination compared with the original MRC-ICU 1.0 across outcomes and datasets. The performance of MRC-ICU 2.0 (MRC-ICU 2.1 and 2.2) was generally comparable to established severity-of-illness scores (SOFA and APACHE II), although it did not consistently outperform these measures. When incorporated into combined models, MRC-ICU 2.0 provided additional predictive value, indicating that it captures information complementary to traditional severity-of-illness scores. Overall, these findings suggest that MRC-ICU 2.0 represents an improved and clinically interpretable measure of medication regimen complexity that is useful as a complementary predictor.
OBJECTIVE: To understand why advanced practice midwives (certified nurse-midwives and certified midwives) leave the workforce. STUDY SETTING AND DESIGN: A multi-method, multi-source investigation included secondary analysis of certification data of advanced practice midwives and a cross-sectional online survey with closed- and open-ended items. Advanced practice midwives' active certification data were used to compare self-reported demographic characteristics of advanced practice midwives who reported working in the discipline of midwifery to those who did not (n = 9704). A survey was conducted in 2022 with individuals who allowed their certification to lapse between 2017 and 2021 (n = 303) and individuals who maintained certification but reported not working in the discipline of midwifery (n = 1994) to understand why individuals left the workforce and the likelihood of returning. Data were analyzed with ANOVAs, chi-squares, t-tests, and thematic analysis. DATA SOURCES AND ANALYTIC SAMPLE: Administrative data from the American Midwifery Certification Board (n = 9704) and an online survey from a national sample of currently and previously certified nurse-midwives and certified midwives who had left the workforce (n = 646; response rate of 33.8%). PRINCIPAL FINDINGS: The most endorsed reasons for leaving were work-life balance (50.3%, n = 325), unsupportive work environment (34.7%, n = 224), and schedule (32.0%, n = 207). Participants from restrictive regulation states reported lack of opportunities for career advancement, state-level regulation restricting ability to practice, and lack of employment opportunities at higher rates. Respondents of color more frequently reported inadequate compensation, lack of opportunity for advancement, and workplace discrimination at higher rates. Themes included barriers to re-entry to practice and compensation. CONCLUSIONS: Work-life balance and work environment drive midwifery workforce attrition. Individuals of color and those living in states with restrictive regulation face unique challenges. Challenges re-entering the workforce after leaving create barriers to remaining in the workforce, especially with inequitable compensation.
INTRODUCTION: Nutritional management of critically ill patients receiving vasopressors is challenging. This survey aimed to describe UK critical care dietitians' practices and confidence regarding the route, timing and dose of artificial nutrition support in critically ill patients receiving vasopressors, and explore relationships of these with intensive care unit (ICU) and dietitian professional characteristics. METHODS: A cross-sectional, anonymous survey was distributed electronically to UK registered dietitians working in ICU via the British Dietetic Association Critical Care Specialist Group and British Society of Parenteral and Enteral Nutrition mailing lists. The 32-item survey included questions regarding ICU and professional characteristics, dietetic practices (artificial nutrition route, timing, and dose), evidence sufficiency and confidence. Data were compared between ICU and professional characteristics and dietetic practice using Fisher's exact or Kruskal-Wallis tests, as appropriate, and with self-reported confidence using Spearman's rank correlation or Kruskal-Wallis. RESULTS: Of 89 responses, 72 met the eligibility criteria. All respondents completing dietetic practice questions (71/71, 100%) used gastric feeding as the first-line artificial nutrition route, and two thirds (47, 66.2%) initiated this within 24-48 h of ICU admission. Over two thirds (39/57, 68.4%) aimed for < 70% energy targets in the first 72 h, with 48 (84.2%) escalating to full targets thereafter. Despite more than three quarters (41/52, 78.8%) feeling confident in managing critically ill patients receiving vasopressors, most considered evidence to be insufficient. There was no significant association between enteral nutrition practices and any ICU or dietitian professional characteristics or self-reported confidence. CONCLUSION: Amongst UK critical care dietitians, there is substantial variation in EN initiation and escalation practices for critically ill patients receiving vasopressors. Despite high self-reported confidence, evidence concerning the route, timing and dose of artificial nutrition was perceived insufficient.
BACKGROUND: Developmental dysgraphia affects 5% to 20% of school-age children and reaches 59% among children with ADHD or autism. The condition produces task avoidance, eroded self-esteem, and behavioral presentations that frequently result in psychiatric referral for anxiety, depression, school refusal, and behavioral disturbance. More than 37% of children with learning disabilities reach clinical thresholds for affective and ADHD problems. Despite this clinical footprint, dysgraphia remains nosologically contested and rarely identified within psychiatric evaluation. OBJECTIVES: This integrative review synthesizes the multidisciplinary evidence on developmental dysgraphia and examines its implications for child and adolescent psychiatric-mental health nursing. DATA SOURCES: Eight databases (PubMed/MEDLINE, CINAHL, PsycINFO, Scopus, ERIC, Cochrane, OTseeker, Web of Science) yielded 8290 records published between January 2000 and March 2026. After deduplication, 6308 records were screened, 1476 were assessed for eligibility, and 56 contributed to synthesis. Synthesis followed Whittemore and Knafl (2005) under PRISMA 2020 reporting conventions. CONCLUSIONS: Findings document definitional disagreement, fragmented assessment, underpowered intervention evidence, and substantial psychosocial burden. Three nursing publications addressed dysgraphia, and none reported original research on the condition. IMPLICATIONS FOR PRACTICE: Dysgraphia screening may be integrated into psychiatric evaluations of children referred for ADHD, anxiety, depression, school refusal, or behavioral disturbance. Handwriting may be monitored as a stimulant medication outcome. On inpatient units, writing-based therapeutic activities require adaptation when dysgraphia is suspected. Pediatric primary care and school health represent upstream identification opportunities.
BACKGROUND: Hemodynamic management after out-of-hospital cardiac arrest (OHCA) is critical, yet the impact of vasopressor-driven mean arterial pressure (MAP) targets on pulmonary circulation and right ventricular (RV) function remains unclear. METHODS: In this substudy of the randomized, double-blinded BOX trial, comatose OHCA survivors were allocated to low (63 mmHg) or high (77 mmHg) MAP targets. Pulmonary artery catheters (PAC) were used for serial hemodynamic assessment for 48 h after Intensive Care Unit admission. The primary endpoint was calculated pulmonary vascular resistance (PVR), secondary endpoints included pulmonary capillary wedge pressure (PCWP), pulmonary artery pulsatility index (PAPi), and RV cardiac power output (RV-CPO)-a measurement of RV pumping function. RESULTS: Among 730 included patients (median time randomization to PAC insertion 1.3 h), mPAP was consistently higher in the high-MAP group (mean difference 1.11-1.71 mmHg, 95% CI range 0.12-2.59). Calculated PVR was transiently lower in the high-MAP group during the first 24 h (mean difference -0.16 to -0.30, 95% CI range -0.31 to 0.11), before converging between groups. RV-CPO was lower in the low-MAP group throughout the observation period (mean difference 0.01-0.04 W [95% range 0.00-0.07], with the largest difference at 48 h. PCWP decreased in both groups but was significantly lower in the low-MAP group during the first 12 h (mean difference 1.06-1.40 mmHg, 95% CI range 0.25-2.38). CONCLUSIONS: In comatose OHCA survivors, targeting a higher MAP increased pulmonary artery pressures, PCWP, RV-CPO, heart rate, and cardiac output. The proportionally greater increase in cardiac output over pulmonary artery pressures resulted in a decreased calculated PVR. TRIAL REGISTRATION: ClinicalTrials.gov identifier: NCT03141099. EDITORIAL COMMENT: In this secondary analysis of a subgroup in the BOX out of hospital cardiac arrest treatment trial for oxygen level targets, blood pressure treatment target levels, higher or lower were analyzed, including central circulatory outcomes, using a pulmonary artery catheter. The higher blood pressure target group had accompanying higher pulmonary artery pressures and cardiac output, with initially a small reduction in calculated pulmonary vascular resistance.
Mental health nursing requires specialised training in therapeutic communication and related soft skills. Innovative, digitally enhanced strategies may support competency development, particularly amid clinical placement shortages. This article outlines insights from a scoping review of technology use in undergraduate mental health nursing education. The objectives were to (a) explore the impact of using these technologies in students' experience and (b) develop insights that can contribute to the development of a curriculum that embed innovative educational technology with strong theoretical foundations and pedagogical strategies. This review was guided by the modified Arksey and O'Malley methodological framework. The PCC (Population, Concept, Context) framework was used to formulate the eligibility criteria. A review protocol was registered with the Open Science Framework (OSF). The databases for searching included CINAHL, MEDLINE, Scopus, PsycINFO, Web of Science. The results were reported according to the PRISMA-ScR checklist. The review included 35 studies and the evidence showed that, virtual reality simulations (VRS) with varying immersive abilities were the most popular innovative educational technology used in undergraduate mental health nursing education. Interestingly, no articles were identified that used other innovative educational technologies as outlined in the search strategies. Both immersive and non-immersive VRS were equally effective in improving student learning experiences compared to traditional learning modalities. The main benefits included enhanced learning experiences and comprehension and the development of necessary skills and confidence before entering clinical settings. Advanced technologies offer future-focused benefits for mental health nursing education; however, core therapeutic skills remain essential. Virtual learning should therefore complement, not replace, realistic learning experiences.
The Safewards model and its ten interventions have been effective in reducing restrictive practices and preventing conflict within acute inpatient mental health units. However, few studies in the current literature explore the consumers' experiences of Safewards. This exploration also needs to consider the views of Mental Health Nurses and the Lived Experience Workforce, who are both important stakeholders in the application of Safewards and how it impacts on consumers' experiences. Despite this, the views of Mental Health Nurses and the Lived Experience Workforce about consumers' experiences of Safewards are limited. This qualitative study explored the views of Lived Experience Workforce leaders about consumers' experiences of Safewards, and Mental Health Nurses' responses to these experiences in acute inpatient mental health units in Australia. Six Lived Experience Workforce leaders participated in individual interviews. Data were analysed using thematic analysis, revealing four themes: (1) consolidating Safewards through understanding consumers' experiences, (2) consumers as leaders in Safewards, (3) acknowledging the realities of acute inpatient mental health units and (4) practice foundations underpinning Safewards. Results highlighted the positive impact of improved consumer involvement in Safewards. Additionally, mechanisms to develop strategic partnerships between Lived Experience Workforce leaders and mental health nurses warrant further investigation. This study highlighted the restrictive nature of acute inpatient mental health units and the need to acknowledge the impact this has on consumers. Further embedding of foundational approaches, such as trauma-informed and recovery-oriented practice within Safewards, is also required to align with consumers' expectations. Greater recognition of consumers' experiences and their agency within the model, and consideration of other Safewards interventions, is also needed. This is required to increase safety, reduce harms associated with restrictive practice, and enhance Safewards effectiveness.
As community mental health services expand in scope and responsibility, mental health nurses are playing a central role in delivering integrated, recovery-oriented care. However, they face substantial challenges in adapting to community practice and sustaining professional development. Clinical supervision can mitigate these demands through its formative, normative, restorative functions. This study explored the supervision experiences of community mental health nurse specialists in South Korea to provide evidence for specifying the effective functions and operational systems of supervision using an exploratory qualitative design. Twelve community mental health nurse specialists participated in three focus group interviews conducted between June 2024 and July 2025. Data were analysed using reflexive thematic analysis. Four themes and 10 subthemes were generated: translating community mental health ideals into professional practice; serving as an anchor in unfamiliar terrain; supervision undermined by superficiality and disrespect; and competency development constrained by structural barriers. Supervision was perceived as a critical space for clarifying clinical direction, regulating emotional involvement and supporting professional adaptation. However, formalistic delivery and structural constraints limited its impact. These findings highlight the need for integrated and systematic supervision approaches aligned with the community mental health paradigm, supported by organisational and policy commitments to protected time, staffing, education and financial resources. Strengthening supervision under such conditions may enhance practitioner development and service user outcomes.
Interventions aimed at reducing restrictive practices are also designed to enhance the service experience in acute mental health units. However, people with experience of coercive engagement with these services are seldom involved as active contributors in evaluative research on interventions to reduce restrictive practices. With the meaningful involvement of lived experience practitioners, this research was aimed at examining care recipients' service experiences and perspectives on nurses' therapeutic responses during the implementation of a de-escalation intervention in three adult inpatient units within New South Wales, Australia, from March 2024 to April 2025. Nested within a larger study employing a mixed concurrent control design, this research evaluated the effectiveness and process of the Safe Steps for De-escalation through comparisons of unmatched measures of empowerment, dehumanisation, and staff actions on violence prevention across three time points, as well as through a reflective thematic analysis of semi-structured interviews. Safe Steps is a structured approach for therapeutic responding, targeting nurses' relationship-promotion behaviours to increase focus on minimising the use of restrictive practices. Eighty-six inpatients completed the unmatched measures, with nine participating in interviews following discharge. No significant changes were noted in quantitative measures over time. Five themes emerged from the qualitative analysis: (i) Clarity calms; confusion harms, (ii) Control cuts deep, (iii) Systems strain; people break, (iv) Connection is treatment in itself, and (v) Meaning-making outweighs medicine. These findings cast acute inpatient units in a light akin to a power circuit, elevating the need to make inpatient admissions more reflective of everyday life outside the units.
BACKGROUND: Acute kidney injury (AKI) is common in the intensive care unit (ICU) and associated with increased mortality. While diuretics are widely used to manage fluid accumulation, their impact on survival in established AKI remains uncertain. METHODS: This retrospective cohort study included adult ICU patients with AKI present on or within 48 h of ICU admission in the Capital Region of Denmark, 2022-2024. Early diuretic exposure was defined as systemic diuretic administration within 24 h after AKI onset. Primary outcome was 30-day mortality, analyzed using 24-h landmark Cox regression adjusted for sex, Simplified Acute Physiology Score 3 (SAPS 3), baseline creatinine, and AKI stage. Pre-specified subgroup analyses by AKI stage and post hoc sensitivity analyses were performed. Secondary outcomes included fluid accumulation (> 5% ideal body weight) and Major Adverse Kidney Events within 30 days (MAKE30). RESULTS: Of 4430 patients with AKI, 58% received early diuretics. In the primary adjusted analysis, early diuretics were not associated with 30-day mortality (hazard ratio (HR) 1.11, 95% confidence interval (CI) 0.98-1.26, p = 0.113). In a post hoc time-dependent sensitivity analysis, diuretic use was associated with higher mortality (HR 1.27, 95% CI 1.08-1.49, p = 0.004). In the pre-specified AKI stage 3 subgroup, early diuretic use was associated with a higher risk of mortality (HR 1.42, 95% CI 1.16-1.73, p < 0.001). Diuretics were associated with a lower risk of fluid accumulation (odds ratio (OR) 0.58, p < 0.001) but a higher risk of MAKE30 (OR 1.23, p = 0.004). CONCLUSION: Early diuretic treatment was frequent but not associated with improved survival in the primary analysis. Given the observational design, causal relationships cannot be inferred from these findings. These results do not support routine early diuretic use in unselected AKI patients; prospective studies are needed to clarify the role of targeted diuretic therapy in patients with fluid accumulation. EDITORIAL COMMENT: This retrospective cohort analysis analyzes associations between acute renal injury development in intensive care unit patients and early diuretic use, along with fluid balance. Early diuretic use was not associated with improved survival in this cohort, where treatments were uncontrolled. Risks are described by renal injury severity subgroups and renal outcomes after ICU.
There are increasing guides and expectations for being trauma informed in research practices. This perspective paper builds upon this emerging field of literature to consider what it means to be trauma and violence informed in mental health nursing research and evaluation. Being trauma and violence informed requires all the same in-the-moment application of the principles of trauma informed care when engaging with participants or data, while also contextualising trauma in the context of wider social contexts. This includes recognising the role that structural violence plays in compounding and sustaining trauma for groups and individuals. To be trauma and violence informed in research requires attention to the power that research and evaluation hold and ongoing reflection on the implications of the design, measures, outcomes and findings of research and evaluation, while informing all decisions by awareness of trauma and the forms of violence that cause and sustain it.
BACKGROUND: Turnover among healthcare workers (HCWs) is highly prevalent in intensive care units (ICUs). Due to demanding workloads, stressful conditions, and increasing pressure to work more efficiently, this problem is likely to persist. Consequently, implementing proactive strategies to support HCWs retention is needed. This study aimed to examine associations between work environment factors and ICU HCWs' intentions to quit. METHODS: Based on data from a prospective, open-cohort, multicenter study of hospital frontline workers conducted during the four main waves of the COVID‑19 pandemic in Norway, we analyzed self-reported data from HCWs who completed the final survey, which included two outcomes relevant to turnover: (1) frequent thoughts of quitting and (2) intention to look for a new job. A work-environment -factor tool assessing occupational risk and characteristics in emergencies (FORCE-index). Hierarchical linear regression was used to examine associations between work environment factors and the two turnover outcomes. RESULTS: Among 977 frontline HCWs (median age 45 years, 75% women, median 16 years of work experience), several work environment factors showed protective association with turnover intention. Across both outcomes, familiarity with colleagues and surroundings and social support from colleagues and immediate superiors were the most important protective factors, linked to fewer thoughts of quitting and a lower intention to seek a new job. For frequent thoughts of quitting, additional protective factors included better stress management, workload manageability, infection safety, and social safety. Younger age was a consistent risk factor for both outcomes, while working in the ICU and experiencing morally distressing situations were specifically associated with thoughts of quitting. Pandemic exposure variables were not significantly associated with either outcome. CONCLUSION: Turnover intention among ICU HCWs at four Norwegian university hospitals during the fourth time point of the COVID‑19 pandemic was associated with work environment factors. Work in the ICU, younger age, and morally distressing experiences were associated with frequent thoughts of quitting, whereas several work environment factors were protective. Familiarity and social support were also protective against actively looking for a new job, suggesting that strengthening these factors may be particularly important for reducing turnover intention and retaining HCWs in the ICU.
BACKGROUND: Feeding intolerance is common in intensive care unit (ICU) patients, but evidence supporting prokinetic use is limited. We aimed to provide international epidemiological data on the use of prokinetic agents in adult ICU patients and to explore potential associations with patient-important outcomes. METHODS: We conducted an inception cohort study between August 2024 and March 2025 in acutely admitted ICU patients in 56 ICUs across 11 countries. The primary outcome was the proportion of patients receiving prokinetic agents. Secondary outcomes included associations with baseline characteristics, serious adverse events (SAEs), days alive out of ICU/hospital, days alive without life support and 90-day mortality. Associations with SAEs, baseline characteristics and mortality were assessed using pre-specified Cox regression models, while other secondary outcomes were evaluated using adjusted linear regression. All models were adjusted for country, severity of illness, number of comorbidities, surgery and ICU admission type. RESULTS: Among 1440 ICU patients (median age 64 years, 56.9% male), 187 (13.0%; 95% confidence interval [CI] 11.3-14.8) received prokinetic agents during ICU stay, most commonly metoclopramide (65%). Prior abdominal surgery was associated with the initiation of prokinetic agents (hazard ratio [HR] 1.81; 95% CI 1.17-2.79). Use of prokinetic agents was statistically significantly associated with a higher hazard of experiencing a SAE (HR 1.9; 95% CI 1.3-2.8), fewer days alive out of ICU (mean difference [MD] -7.6 days; 95% CI, -13.4 to -2.2) and hospital (-13.5 days; 95% CI -18.7 to -8.4), but not with 90-day mortality (HR 0.62; 95% CI 0.3-1.2). CONCLUSIONS: Prokinetic agents were used in 13% of ICU patients, most commonly metoclopramide and more often in those with prior abdominal surgery. Prokinetic use was associated with a higher hazard of experiencing SAEs and fewer days alive out of hospital/ICU.
AIM: Preterm birth, defined as delivery at gestational age less than 37 weeks, is a major contributor to neonatal morbidity, placing a significant burden on healthcare resources. This analysis explores the prevalence and patterns of critical care admissions among preterm neonates in England. METHODS: Hospital-level data were obtained from the Hospital Episode Statistics Data-NHS England 2022-2023 database. Data were analyzed for newborns in England for April 2022-March 2023, focusing on gestational age categories and the care level of facilities managing these infants. RESULTS: Among all 541,765 singleton births in England during the examined interval, 7.0% (37,815) were preterm. Of these preterm infants, 71.3% (26,965) had a recorded gestational age. Of those with recorded gestational ages, 0.6% (149) were born <28 weeks (extremely preterm), 10.5% (2,844) at 28-32 weeks (very preterm), and 88.9% (23,972) at 33-37 weeks (moderate and late preterm). While 58.4% (87) of extremely preterm neonates were delivered in a hospital with appropriate facilities, 32.2% (48) of extremely preterm neonates, and 4.3% (121) of very preterm neonates were born in hospitals without neonatal intensive care facilities. CONCLUSION: Persistent gaps in triage for women at risk of preterm birth highlights the need for improved early risk recognition and in utero referral systems to ensure appropriate delivery in recommended critical care facilities and to reduce postnatal transfers for babies.
Accurate and timely mortality prediction is essential for nursing clinical decision-making in intensive care units (ICUs). Although the Sequential Organ Failure Assessment (SOFA) score is widely used to evaluate organ dysfunction, its manual calculation limits routine application in fast-paced clinical environments. This study aimed to enhance ICU system-level safety and workflow efficiency by refining and evaluating an automated Electronic Medical Record (EMR)-integrated SOFA scoring system (AI-SOFA) to evaluate: (1) its predictive performance for mortality compared to traditional manual scoring; and (2) its clinical utility as a nursing informatics initiative. A retrospective cohort study was conducted using EMR data from 2559 ICU admissions at a tertiary hospital in South Korea. Automated SOFA scores were generated using 11 routinely collected clinical parameters. Logistic regression, random forest, and XGBoost models were trained, and model performance was evaluated using the area under the receiver operating characteristic curve (AUROC), sensitivity, specificity, accuracy, and F1 score. ICU mortality increased markedly with higher SOFA scores, exceeding 50% at scores ≥13. Among the machine learning (ML) models, XGBoost demonstrated the highest predictive performance (AUROC=0.9005), outperforming random forest (0.8975) and logistic regression (0.8722). In contrast, mortality prediction based on manual SOFA scoring showed substantially lower accuracy (AUROC=0.64). The AI-SOFA system serves as a nursing informatics tool that supports nursing workflows by enabling real-time risk stratification, reducing documentation burden, and facilitating timely clinical decision-making in ICU settings.
INTRODUCTION: Midwifery, which used to be practiced with knowledge passed down from generation to generation, has now gained a professional identity through education. This study examines global trends in midwifery education research using bibliometric methods. METHODS: In the study, we analyzed 1029 studies published in the Web of Science database on midwifery education between 1993-2023. Bibliometric and visualization analyses revealed the general structure of the literature by determining important trends, thematic research areas, the most influential publications, journals, and countries in midwifery education. RESULTS: According to the results of the analysis, studies on midwifery education have increased significantly in recent years. The increase in publications appears to coincide with the growing prominence of topics such as digitalization, simulation-based learning, and distance education in the literature. Australia stands out as one of the most influential and productive countries in the field of midwifery education. In addition, the continuing care model and simulation-based learning in midwifery were among the most frequently studied topics. DISCUSSION: The study identifies research trends, priority research areas, and areas for development in midwifery education. The findings provide important insights for the development of midwifery education programs, the support of policymakers' decision-making processes, and the identification of future research priorities.
BACKGROUND: The United States declared endemic measles eliminated in 2000. However, outbreaks continued, with resurgences in 2019 and 2025. In 2025, more than 2200 cases across 48 outbreaks, the most since 1992, were reported. In the first half of 2026, 2073 cases were reported. Declining measles, mumps, and rubella vaccination rates have increased susceptibility among children. Acute and critical care nurses are central to early recognition and management of measles for optimal outcomes. OBJECTIVE: To summarize current evidence on measles epidemiology, pathophysiology, clinical presentation, complications, treatment strategies, and acute and critical care nursing implications, emphasizing preparedness amid rising case numbers. METHODS: A literature review was conducted using PubMed and CINAHL databases and websites of Centers for Disease Control and Prevention, World Health Organization, professional organizations, and pediatric hospitals. English-language sources published from 2015 to August 2025 were prioritized; relevant earlier studies were included. Reference lists were searched for additional articles. DATA SYNTHESIS: Measles is among the most contagious human diseases. Typical features include fever, cough, coryza, conjunctivitis, and morbilliform rash. Severe respiratory and neurological complications may require critical care hospitalization. Complications like encephalitis may present weeks to years after acute infection. Management remains supportive, with vitamin A supplementation recommended. Acute and critical care nursing priorities include early recognition, isolation precautions, specimen collection, respiratory and hemodynamic support, neurological monitoring, serial assessments, hydration, nutrition, and caregiver education. CONCLUSION: Measles is resurging in the United States despite being vaccine preventable. Nurse preparedness, including knowledge of clinical features, complications, and infection control, is essential to mitigate morbidity and mortality and to support outbreak prevention. (Critical Care Nurse. Published online ahead of print July 17, 2026).
INTRODUCTION: Critical care nursing includes physically, emotionally, and ethically challenging jobs which can induce role conflict and organizational cynicism amongst other organizational attitudes. This research aimed to evaluate the association between role conflict and organizational cynicism among critical care nurses. METHODS: This cross-sectional study recruited 322 nurses working in intensive care units of hospitals under Tehran University of Medical Sciences who completed Role Conflict Questionnaire by Rizzo et al., and Organizational Cynicism Questionnaire by Dean et al. The data were analyzed through Spearman correlation test and multiple linear regression analysis. RESULTS: The mean age of participants was 36.26 ± 8.61, and 73.6% were women. Role conflict had a mean score of 2.58 ± 0.83 and organizational cynicism of 2.73 ± 0.96, showing moderate level of both variables. A significant positive correlation was found between role conflict and organizational cynicism (r = 0.765, p < 0.01) as well as with its emotional, cognitive, and behavioral components. Multiple job holding and number of workplaces at one time were identified as the main factors for both variables. CONCLUSION: There exists a high association between role conflict and organizational cynicism among critical care nurses. CLINICAL TRIAL NUMBER: Not applicable.
BACKGROUND: Among Hispanic undergraduate students, the association between research-related coursework and research interest remains largely underexplored. This exploratory study examined differences in research interest among undergraduate nursing students according to their exposure to research-related coursework, drawing on Social Cognitive Career Theory. METHODS: A cross-sectional study was conducted with 106 nursing students from a Peruvian university. Participants completed the Interest in Research Questionnaire (IRQ), which demonstrated excellent internal consistency (α = 0.98). Research interest was compared across four academic-semester groupings reflecting proximal and distal exposure to research-related coursework using rank-based nonparametric methods. RESULTS: Significant differences in research interest were observed across groups (Anderson-Darling test = 9.41, p = 0.001), indicating a curvilinear pattern. Students currently or recently exposed to research-related coursework (levels 2 and 4) reported significantly higher research interest than those with more distal exposure (level 3; p < 0.05; medium effect sizes). First-semester students showed research interest levels comparable to those of the proximally exposed groups. CONCLUSION: Research interest may decline in the absence of sustained engagement in research activities, underscoring the importance of early and continuous integration of research experiences throughout undergraduate nursing curricula. The findings also provide initial evidence supporting the use of the IRQ in Spanish-speaking undergraduate contexts.
BACKGROUND: In 2015, the child mortality rate in Laos was 53.6 per 1,000 live births. The Lao Friends Hospital for Children (LFHC) in Luang Prabang was established to enhance access to specialized pediatric care. To support workforce development, a Pediatric Nursing Training Program was implemented. However, the program has not undergone a formal evaluation since its inception. This study aims to evaluate the program's first five years. STUDY DESIGN: The evaluation included a review of curriculum documents via an online platform and feedback collection through an online survey administered to former expatriate nurse volunteers who provided clinical mentorship. Additionally, semi-structured interviews were conducted with former nurse leaders who designed and implemented the program. Qualitative data were analyzed thematically and validated through triangulation. RESULTS: The curriculum review revealed system-based and course-specific plans, including clear objectives, teaching methods, and evaluation tools. Of the 148 clinical mentors surveyed, a 45% response rate was achieved. Survey responses indicated improvements in nurses' clinical skills since the program's inception, with mentors emphasizing the importance of cultural attunement to Lao staff. Six out of seven former nurse leaders participated in interviews. Key themes emerged, highlighting the value of culturally relevant educational materials, multimodal teaching strategies, a train-the-trainer approach, and clinical mentorship as integral components of the program. CONCLUSION: The development of pediatric nursing specialization at LFHC was facilitated by structured curriculum plans, cultural sensitivity, diverse teaching methodologies, and robust clinical mentorship. These findings provide valuable insights for designing culturally competent and sustainable training programs in Laos and similar contexts.
BACKGROUND: Cerebrovascular diseases represent a major public health challenge, and stroke is among the leading causes of mortality worldwide. Among poststroke complications, pneumonia stands out because of its frequency and negative impact on clinical outcomes, including prolonged hospitalization and increased mortality. In this context, studies investigating the risk factors associated with stroke-related pneumonia differ in terms of their design, care setting, and adopted definitions. OBJECTIVE: This study aims to map risk factors related to the incidence of pneumonia in adults hospitalized after stroke. METHODS: This scoping review protocol was developed in accordance with the JBI Reviewer's Manual and the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews). Searches will include the following indexed databases: PubMed (MEDLINE), Embase, Scopus, the Cochrane Library, Web of Science, and the Virtual Health Library. Gray literature will be searched in Google Scholar, the CAPES Theses and Dissertations Catalog, the Brazilian Digital Library of Theses and Dissertations, ProQuest, SciELO Preprints, medRxiv, ClinicalTrials.gov, and the Brazilian Registry of Clinical Trials. Additional organizational sources will include the World Health Organization, the Pan American Health Organization, the Centers for Disease Control and Prevention, the European Stroke Organisation, and the Brazilian Ministry of Health. Qualitative, quantitative, and mixed methods studies, including observational and experimental designs, will be considered, with no language or time restrictions, provided that they meet the eligibility criteria defined in the protocol. Study selection will follow 3 stages using Mendeley (Elsevier) and Rayyan (Rayyan Systems Inc). RESULTS: This protocol was funded in June 2026 by the Federal University of Mato Grosso do Sul and the Coordination for the Improvement of Higher Education Personnel (Finance Code 001). The protocol was developed and prospectively registered in the Open Science Framework. Preliminary searches were carried out in August 2025 in PubMed (MEDLINE), Embase, and the Cochrane Library to test the sensitivity of the search strategies and estimate the potential volume of eligible studies. At the time of publication, the final search, study selection, data extraction, and evidence synthesis had been completed. The manuscript reporting the final review results is expected to be submitted for publication in early 2027. CONCLUSIONS: This review is expected to contribute to the systematization of evidence on risk factors related to stroke-associated pneumonia, identify knowledge gaps, and support future prevention strategies and clinical management of hospitalized patients. TRIAL REGISTRATION: Open Science Framework 10.17605/OSF.IO/EXYWZ; https://osf.io/exywz/overview. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/90248.
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BACKGROUND: Polypharmacy is often crucial for managing complex and treatment-resistant psychiatric disorders, yet it carries risks such as adverse drug interactions, medication non-compliance, and suboptimal health outcomes. Interprofessional perspectives on polypharmacy significantly influence clinical decision-making and prescribing practices. AIM: This research evaluates healthcare providers' knowledge and attitudes regarding psychiatric polypharmacy, comparing the views of psychiatric nurses, psychiatrists, and pharmacists. It also explores how these factors impact prescribing behaviors and interprofessional collaboration. METHODS: A convergent mixed-methods approach was employed at the Erada Complex for Mental Health and Addiction in Jeddah, Saudi Arabia. The study involved 221 healthcare providers, including psychiatrists (n = 32), psychiatric nurses (n = 158), and pharmacists (n = 31). Quantitative data were collected using validated scales to assess knowledge and attitudes, while qualitative insights were gathered through open-ended responses and group discussions. RESULTS: Knowledge levels varied among the professionals, with psychiatrists possessing the most comprehensive understanding (84.2 ± 11.0), followed by pharmacists (81.5 ± 10.0) and psychiatric nurses (79.5 ± 9.8). Attitudes toward polypharmacy also differed, with psychiatrists showing the most favorable views (3.79 ± 0.49), whereas nurses and pharmacists were more cautious due to concerns about adverse effects and medication burden. A significant positive correlation (r = 0.653, p < 0.05) was observed between knowledge and attitude scores. Sociodemographic factors, such as professional experience and confidence in medication management, influenced both knowledge and attitudes regarding medication management. Qualitative findings highlighted interprofessional tensions, with psychiatric nurses advocating for more conservative approaches, psychiatrists emphasizing clinical necessity, and pharmacists focusing on optimizing medication safety. CONCLUSION: Healthcare providers demonstrated varying levels of awareness and attitudes toward psychiatric polypharmacy, shaped by their professional roles and responsibilities. While psychiatrists were more accepting of polypharmacy, psychiatric nurses expressed concerns about patient burden, and pharmacists prioritized safety considerations. Enhancing interprofessional collaboration and ongoing education on polypharmacy practices are essential for improving patient outcomes.
INTRODUCTION: Spirituality, recognized as an essential aspect of nursing care, contributes to well-being and resilience in critical care settings. Its integration into practice strengthens the meaning and sense of meaning and purpose in the lives of nursing professionals. OBJECTIVE: To systematically review the evidence on spirituality among nursing professionals working in critical healthcare settings. METHODOLOGY: A systematic review and meta-analysis were conducted following the PRISMA guidelines. The protocol was registered in PROSPERO (CRD42023371984). Searches were performed from inception to april 2024 in the following databases: Medline/PubMed, Embase, Lilacs, Cochrane CENTRAL, and Web of Science. The meta-analysis of individual means was performed using a random-effects model. Untransformed means (MRAW) were used to estimate the 95% confidence intervals of individual studies, while the I2 and tau2 statistics assessed heterogeneity. RESULTS: A total of 1175 studies were identified, 34 of which were included in the systematic review and 4 in the meta-analysis. A prevalence of 58,8% was observed in non-experimental quantitative studies, with "spirituality education and meeting spiritual needs" being the main theme. Meta-analyses were conducted on studies using scales to assess spirituality levels, particularly the Spiritual Care Competence Scale (SCCS), which showed the best performance with an MRAW of 98,56 (IC 95%: 97,86; 99,25; I2: 0,0%), indicating a moderate level of competence in spiritual care. CONCLUSIONS: The findings highlight the importance of spirituality in professional performance in critical care settings, emerging as a key component for promoting well-being by strengthening resilience in the face of caregiving challenges.