Attitudes, perceptions, behaviours, and concerns of patients listed for kidney transplantation during the COVID-19 pandemic.

چکیده اصلی

BACKGROUND: The COVID-19 pandemic caused major disruptions in solid organ transplantation worldwide, particularly in kidney transplantation. Patients on deceased-donor kidney transplant waiting lists represent a vulnerable population due to ongoing dialysis requirements and concerns regarding immunosuppression and infection risk. OBJECTIVE: This study aimed to evaluate the attitudes, behaviors, and concerns of patients on the deceased-donor kidney transplant waiting list regarding kidney transplantation during the second wave of the COVID-19 pandemic. METHODS: A cross-sectional, telephone-based survey was conducted between October and December 2020 at one tertiary care centre in Turkiye. The survey assessed adherence to preventive measures, COVID-19 exposure history, perceptions of renal replacement therapy modalities, attitudes toward kidney transplantation, and transplantation-related concerns during the pandemic. Demographic and clinical data were collected, and responses were analyzed using appropriate statistical methods. RESULTS: A total of 188 transplant candidates (mean age 47.3 ± 13.1 years; 56.4% male) were included. Adherence to preventive measures was reported by 99.5% of participants, and 80.9% followed quarantine rules. Although 76% of participants preferred kidney transplantation before the pandemic, this rate decreased to 55.3% during the pandemic. Despite this decline, 86.7% of participants stated that they would accept a deceased-donor kidney transplant if offered during the pandemic. Only 38.3% reported concerns about undergoing transplantation, with the most common concerns being infection risk related to immunosuppressive therapy, hospital-acquired COVID-19, and donor-related transmission. Shorter renal replacement therapy duration and preemptive transplant status were associated with more favorable attitudes toward transplantation during the pandemic. CONCLUSIONS: Despite pandemic-related uncertainties and concerns, most patients on the deceased-donor kidney transplant waiting list demonstrated a willingness to proceed with kidney transplantation and showed high adherence to preventive measures. These findings highlight the importance of patient education, infection-control strategies, and transparent communication to ensure the sustainability of kidney transplant programs during current and future pandemics.

ترجمه فارسی چکیده

پاندمی کووید-۱۹ باعث اختلالات جدی در پیوند اعضای جامد در سراسر جهان، به‌ویژه در پیوند کبد شد. بیماران در فهرست انتظار پیوند کبد اهداکننده، جمعیتی آسیب‌پذیر را تشکیل می‌دهند. این مطالعه به ارزیابی نگرش‌ها، رفتارها و نگرانی‌های بیماران فهرست‌شده در مورد پیوند کبد در موج دوم پاندمی پرداخت. یک مطالعه مقطعی مبتنی بر تلفن در یک مرکز مراقبت‌های تخصصی ترکیه انجام شد. نتایج نشان داد که ۹۹.۵٪ از شرکت‌کنندگان به اقدامات پیشگیرانه پایبند بودند و ۸۰.۹٪ قوانین قرنطینه را رعایت کردند. اگرچه ۷۶٪ ترجیح می‌دادند قبل از همه‌گیری پیوند کنند، این نرخ به ۵۵.۳٪ کاهش یافت. با این حال، ۸۶.۷٪ بیان کردند که در صورت پیشنهاد، پیوند کبد اهداکننده را می‌پذیرند. تنها ۳۸.۳٪ نگرانی در مورد پیوند داشتند. مدت زمان کمتر درمان جایگزینی کلیوی و وضعیت پیشگیرانه پیوند با نگرش‌های مطلوب‌تری مرتبط بود.

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