PubMedدسترسی آزاد2026
A window into veterinary imaging.
Emma Corbett, veterinary surgeon and head of imaging at Pennard Vets, shares what drew her to diagnostic imaging: the skills required, the mentors and the day-to-day reward of clearer answers.
زیرشاخه پژوهشی
جستوجوی چندمنبعیدامپزشکی
مقالهها، منابع و پژوهشهای تازه حوزه دامپزشکی
مقالهها
مرتبشده بر اساس تازگیPubMed2026
A message from the new CSCI President, Dr. Chandrakant Tayade.
[Formula: see text] Dr. Tayade earned a Doctor of Veterinary Medicine, Masters, and PhD in Immunology from the Indian Veterinary Research Institute. He then completed a postdoctoral fellowship at the University of Guelph. He joined Queen's University in 2009 as an Assistant Professor and is currently working as a Vice Dean, and the Director of MD PhD Program in the Faculty of Health Sciences. The central theme of Dr. Tayade's research focusses on how immune dysfunction contributes to endometriosis pathophysiology, and identifying immune-based markers for diagnostic and therapeutic interventions. Dr. Tayade has published over 100 peer-reviewed articles in journals such as JCI Insight, Journal of Immunology, American Journal of Pathology, American Journal of Obstetrics and Gynecology, and Trends in Molecular Medicine. He has received competitive funding from the Canadian Institutes of Health Research (CIHR), the Natural Sciences and Engineering Research Council of Canada (NSERC), and the Endometriosis Foundation of America; and industrial funding from Bayer, Aurinia Pharmaceutical, and AbbVie. For his outstanding contributions to research, Dr. Tayade has received numerous special recognitions. In 2012, he won both the Early Researcher Award from the Ministry of Research and Innovation, as well as the Christian J Herr Award for Outstanding Contributions in Reproductive Immunology from the American Society for Reproductive Immunology. In 2014, he earned the Mihran and Mary Basmajian Award for Research Excellence from the Queen's Faculty of Health Sciences.
PubMed2026
BVA at FVE in Finland.
BVA's director of policy and governance, Amelia Findon, reports from the recent Federation of Veterinarians of Europe (FVE) general assembly in Rovaniemi, Finland, where, alongside RCVS, we form the UK delegation.
PubMed2026
Putting the spotlight on spot-on treatments.
Martha Rushbrooke, parliamentary veterinary intern to Lord Trees, discusses the House of Lords select committee investigating the environmental impact of veterinary parasiticides.
PubMedدسترسی آزاد2026
Evaluation of the Utilization Pattern of Veterinary Drugs in Selected Veterinary Clinics of Mekelle City, Tigray, Ethiopia.
BACKGROUND: Currently, a wide variety of pharmaceutical agents are marketed, but only a minority are authorized for use in animals with specific indications. Many veterinary professionals prescribe and administer medications based only on a tentative diagnosis, without first confirming the exact disease or condition. OBJECTIVES: This study aimed to evaluate the utilization patterns of veterinary drugs across different animal species and to identify factors associated with inappropriate drug use in selected veterinary clinics of Mekelle City, Ethiopia. METHODS: A cross-sectional study was conducted from April to October 2024 in three veterinary clinics (Clinic A, Clinic B, and Clinic C) in Mekelle City. The data were collected from case registration books and through a questionnaire survey administered to 15 veterinary clinicians. Information on prescribed drugs, diagnostic practices, and prescribing factors was analyzed using descriptive statistics, chi-square tests, and logistic regression methods. RESULTS: A total of 2183 drug products were prescribed for 1800 animal patients during the study period. Antimicrobials were the most frequently prescribed drug category, accounting for 55.3% of all prescriptions, followed by anthelmintics (21.2%) and other drugs (16.0%). Among antimicrobials, oxytetracycline (81.1%) and pen-strip (13.5%) were the most commonly prescribed drugs, while ivermectin (74.5%) was the predominant anthelmintic. CONCLUSION: The overall utilization patterns of veterinary medications in the three selected study clinics did not follow recommended guidelines for their use. Therefore, diagnostic accuracy and drug selection should be strengthened by promoting evidence-based diagnosis through better laboratory support and clinical guidelines to minimize tentative diagnoses and poor drug choices.
PubMedدسترسی آزاد2026
Bacteriocins in Veterinary Medicine: From Antibiotic Limitations to Targeted Solutions.
Antimicrobial resistance (AMR) has emerged as one of the foremost global threats to public health, with the veterinary sector, responsible for nearly three-quarters of global antimicrobial consumption, representing an underappreciated epicenter of this crisis. Despite the extensive literature on bacteriocins as antibiotic alternatives, most reviews focus on human medicine or food preservation, leaving a conspicuous gap in evidence specific to veterinary medicine. The present review addresses this gap by examining the molecular basis of bacteriocin activity (lipid II, bacterial RNA polymerase, cytoplasmic membrane), strategies for clinical deployment (topical therapy, antibiotic combinations, disruption of biofilm tolerance), and preclinical evidence relevant to bovine mastitis, canine pyoderma and otitis externa, and infections caused by multidrug-resistant pathogens (MRSA (Methicillin-Resistant Staphylococcus aureus), MRSP (Methicillin-Resistant Staphylococcus pseudintermedius), colistin-resistant P. aeruginosa, XDR (extensively drug-resistant) Acinetobacter baumannii). Translational barriers-pharmacokinetic, regulatory, and evidentiary-are critically appraised, alongside emerging directions including precision nanocarriers, biofilm-targeted therapies, and the animal microbiota as a reservoir of novel molecules. Bacteriocins represent a promising yet underexploited antibacterial class in response to the escalating AMR crisis in the animal sector.
PubMedدسترسی آزاد2026
What is herd health management? A narrative review.
BACKGROUND: This narrative literature review proposes an improved definition of herd health management and related terms. The role of veterinarians has shifted to a population-level oriented approach which may be denoted herd health management. Herd health management and related terms are used inconsistently in the scientific literature and theoretical deliberations around its practice are lacking. RESULTS: Herd health management was defined as a continuous, cyclic process dealing with planning, implementing, and evaluating decisions aiming to promote herd health, i.e., normal biological function, including homeostasis and the absence of disease among the animals populating a given farm, to achieve the producer's goals regarding productivity, animal health, and externalities. CONCLUSIONS: The paper proposes a theoretical framework describing how herd health management is practiced. Herd health management includes decisions at both strategic, tactical and operational level. The steps involved in tactical decisions are an evaluation of the current situation, defining goals, identifying risks and planning new practices to be implemented and a way to monitor indicators of success.
PubMedدسترسی آزاد2026
Advances and Challenges in the Diagnosis of Vector-Borne Protozoal Infections in Veterinary Medicine.
Vector-borne protozoal infections-including babesiosis, theileriosis, hepatozoonosis, trypanosomosis, and leishmaniosis-impose a substantial burden on livestock and companion animal health worldwide and carry important zoonotic and public health implications. Accurate diagnosis is essential yet challenging, given the diversity of parasite genera, their markedly different tissue tropisms, and the uneven distribution of diagnostic resources across veterinary settings. This review provides an integrated overview of the principal diagnostic approaches available, structured around the biological logic that guides test selection in practice. Microscopic examination remains the first-line method; its strengths and limitations are discussed for intraerythrocytic parasites (Plasmodium spp., Babesia spp., Theileria spp., Cytauxzoon spp.-the latter two with additional extra-erythrocytic schizont stages in leukocytes and tissue macrophages, respectively), leukocyte-associated forms (Hepatozoon spp.), extracellular trypanosomes, and tissue-stage parasites, including emerging applications of artificial intelligence. Serological methods-enzyme-linked immunosorbent assay (ELISA), indirect fluorescence antibody test (IFAT), and point-of-care lateral flow assays-are evaluated for their role in exposure detection, population screening, and international trade certification, with attention to cross-reactivity and the active-versus-past-infection distinction. Molecular diagnostics, encompassing conventional PCR, qPCR, droplet digital PCR, isothermal amplification, and next-generation sequencing, are reviewed with respect to target selection, sensitivity, and point-of-care applicability. Finally, diagnostic challenges are contextualised within a One Health framework, highlighting the fragmentation of veterinary surveillance and the need for integrated, cross-sector approaches to detect emerging threats.
PubMedدسترسی آزاد2026
Recombinant listeriolysin-O as a platform for next-generation vaccines: Mechanisms, immunological evidence, and translational applications in human and veterinary medicine.
Recombinant Listeriolysin O (rLLO), a cholesterol-dependent cytolysin (CDC) derived from Listeria monocytogenes, has gained increasing attention as a novel immunological adjuvant for next-generation vaccine development. rLLO enhances both innate and adaptive immune responses by facilitating controlled endosomal membrane permeabilization, promoting cytosolic antigen delivery, and enabling efficient antigen cross-presentation, leading to robust CD8⁺ T-cell activation. These immunological properties are particularly advantageous for vaccines targeting intracellular pathogens and malignancies. This narrative review synthesizes current experimental, preclinical, and translational evidence on the application of rLLO across diverse vaccine platforms in human and veterinary medicine, including DNA-, protein-, nanoparticle-, and vector-based formulations. Studies addressing infectious diseases, such as tuberculosis, HIV, dengue, and listeriosis, as well as cancer immunotherapy models, are critically examined. Emerging strategies involving fusion proteins, detoxified rLLO mutants, and recombinant delivery systems are highlighted to illustrate advances in formulation design and immunogenic optimization. Despite promising preclinical outcomes, several challenges remain, including the need for comprehensive safety evaluation, dosing and delivery strategy optimization, and regulatory pathway clarification. Addressing these limitations through standardized toxicological assessment and large-scale clinical and veterinary trials is essential for the successful translation of rLLO-based vaccine components. Overall, rLLO represents a versatile and potent immunological tool with significant potential to advance vaccine design in human and veterinary applications.
PubMedدسترسی آزاد2026
Retrospective analysis of teletriage and teleadvice administered to 1,575 dogs with gastrointestinal signs.
BACKGROUND: Veterinary telehealth can provide veterinary care to various species, geographic locations, client demographics, and practice types. Factors influencing the veterinarian decision when teletriage and teleadvice are administered to a large number of dogs with gastrointestinal (GI) signs have not been previously reported. AIM: To report on dogs evaluated via a veterinarian-led teletriage and teleadvice synchronous video service for GI signs to determine factors associated with referral recommendation for in-person emergency (ER) evaluation. METHODS: The number of animals was 1,575 dogs. Case records summarizing video telehealth evaluations of dogs presenting for GI symptoms performed by veterinarians were reviewed, and data on signalment, history, and clinical signs were collected. Visit outcome was recorded as to whether the patient received a recommendation for an in-person ER referral. The primary statistical objective was to determine which variables were significantly associated with ER referral. RESULTS: Overall, 23% of the cases presented were recommended for in-person ER referral. Vomiting was the most common clinical complaint (62%) and was associated with a 50% greater odds of referral recommendation. Diarrhea was present in 43% of patients and was associated with a 31% lower odds of referral. Abdominal distention and lethargy were associated with the greatest increase in odds of referral recommendation (174% and 126%, respectively). Multivariable logistic regression identified that vomiting, lethargy, anorexia, the presence of other clinical signs, and abdominal distention were significantly associated with ER referral, and a current medication history was negatively associated with ER referral. CONCLUSION: Dogs with vomiting alone, with a combination of abdominal distention, or with a combination of lethargy, anorexia, abdominal distention, and other clinical signs, confirmed by a veterinarian-led synchronous video teleadvice and teletriage service, have increased odds of being referred to an emergency facility compared with dogs without these clinical signs.