PubMed چکیده/رکورد

Multimodal Management of Advanced Metastatic Prostate Cancer: Excellent Response Following Resection of Brain Metastasis and 177Lu-PSMA Therapy.

Ghasemali Divband, Hamidreza Amini, Hamid Saeidi Saedi, Seyed A Shahvarani, Pegah Sahafi• 2026• Clinical nuclear medicine
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چکیده اصلی

A 68-year-old man with metastatic prostate adenocarcinoma was treated with androgen-deprivation therapy and chemotherapy. Restaging 68Ga-PSMA PET/CT revealed a PSMA-avid lesion in the left temporal lobe, which was treated with brain radiotherapy. Subsequent PSMA PET/CT showed brain lesion progression and skeletal metastases. He underwent brain lesion resection followed by 4 cycles of 177Lu-PSMA-617, achieving near-complete resolution of skeletal metastasis. This case highlights the importance of multimodal treatment, including 177Lu-PSMA, in managing brain metastasis in prostate cancer.

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کلیدواژه‌ها

PSMAbrain metastasesmetastatic castration-resistant prostate cancerradioligand therapy
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