[Forensic histological assessment of changes in internal organs in generalized viral infection in infants in the first year of life].

چکیده اصلی

OBJECTIVE: Forensic histological assessment and analysis of pathomorphological changes in internal organs during generalized viral infection in infants in the first year of life. MATERIAL AND METHODS: 65 forensic medical examinations performed at the Bureau of Forensic Medical Examination from 2012 to 2024; cytological examination of smears-prints stained according to Pavlovsky's method and histological examination of microspore slides of internal organs stained with hematoxylin and eosin and MSB Zerbino staining technique. RESULTS AND CONCLUSION: Generalization of the infectious process is an important stage in the course of a viral disease in infants in the first year of life. Generalized viral infection is accompanied by pronounced, deep structural changes in the vascular-stromal and parenchymal components of internal organs, accompanied by severe circulatory disorders in the form of extensive hemorrhages, erythrocyte stasis with sludge phenomenon and clot formation in the microcirculatory bed of internal organs. When conducting forensic medical examinations, a combination of results of the cytological and histological research methods allows us to determine viral lesions of internal organs and to assess the severity and prevalence of pathomorphological changes in internal organs that developed as a result of infectious lesions. The complete forensic histological diagnosis is based on clinical data (if available), results of virological testing and severity of pathomorphological changes that have developed in the internal organs during the generalization of the viral infection.

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