[Treatment algorithm: decannulation management in the context of discontinuous weaning from mechanical ventilation in critically ill patients with tracheal cannula].
Tilo Zimmermann, Lars Krüger, Franziska Wefer, Peter Nydahl, Marius Ostermöller, Lisa Peper, Daniel Plaß, André Ramos Y Soto, Richard Schalk, Valery Maurice Kitz, Thomas Mannebach, Tobias Alzen, Pia Kirchhoff, Sarah Köster, Sarah Lohmeier, Anne Oldag, Thomas Kirschning, Oliver Rothaug• 2026• Medizinische Klinik, Intensivmedizin und Notfallmedizin
Critical care nursingDecannulationEvidence-based practiceIntensive care unitsMechanical ventilationPatient safetyTracheal cannulaTracheostomyWeaning from mechanical ventilation
BACKGROUND: The 2019 medication regimen complexity-intensive care unit (MRC-ICU) score is associated with patient outcomes, ICU complications, and critical care pharmacist workload. This score was developed using heuristic component selection and validated in a single-center cohort of 130 ICU patients. We sought to apply data-driven reweighting methodology in a large, multicenter cohort of ICU adults to improve the predictive capabilit…
INTRODUCTION: Nutritional management of critically ill patients receiving vasopressors is challenging. This survey aimed to describe UK critical care dietitians' practices and confidence regarding the route, timing and dose of artificial nutrition support in critically ill patients receiving vasopressors, and explore relationships of these with intensive care unit (ICU) and dietitian professional characteristics. METHODS: A cross-secti…
BACKGROUND: Hemodynamic management after out-of-hospital cardiac arrest (OHCA) is critical, yet the impact of vasopressor-driven mean arterial pressure (MAP) targets on pulmonary circulation and right ventricular (RV) function remains unclear. METHODS: In this substudy of the randomized, double-blinded BOX trial, comatose OHCA survivors were allocated to low (63 mmHg) or high (77 mmHg) MAP targets. Pulmonary artery catheters (PAC) were…
BACKGROUND: Acute kidney injury (AKI) is common in the intensive care unit (ICU) and associated with increased mortality. While diuretics are widely used to manage fluid accumulation, their impact on survival in established AKI remains uncertain. METHODS: This retrospective cohort study included adult ICU patients with AKI present on or within 48 h of ICU admission in the Capital Region of Denmark, 2022-2024. Early diuretic exposure wa…