PubMed2027
Global genomic surveillance has emerged as a foundational pillar of public health in the twenty-first century, enabling real-time tracking of pathogen evolution and informing outbreak response. This chapter examines the strategic architecture of global genomic surveillance, focusing on its application to arboviruses such as chikungunya virus (CHIKV). It explores the integration of genomic data with epidemiological, clinical, and enviro…
PubMed2026
Patients with rheumatic diseases have persistent information needs that are not fully addressed in routine care. We developed and evaluated guideline-grounded, large language model (LLM) chatbots to support patient self-management and education in rheumatology.Ten disease-specific chatbots based on German guidelines were co-developed and deployed through 13 rheumatology centres and six patient organisations. Chatbot users rated respons…
PubMed2026
AI is increasingly incorporated into psychiatric triage, risk prediction, passive monitoring, clinical documentation, and patient-facing conversational systems. These applications may improve access, continuity, efficiency, and pattern recognition, but they also redistribute epistemic authority and complicate responsibility when harm occurs. European regulation is developed in relation to market access, data governance, risk management…
PubMed2026
INTRODUCTION: Routine laboratory panels are nearly universal, but the panels' joint information is underused. We evaluated contemporaneous classification of International Statistical Classification of Diseases, Tenth Revision (ICD-10) code groups from same-encounter laboratory results. METHODS: We developed 17 eXtreme Gradient Boosting (XGBoost) classifiers in 242 648 adult internal medicine encounters using age, sex, and results from …