PubMed چکیده/رکورد

Fibrous Dysplasia With 99m Tc-FAPI Uptake in a Patient Under Long-term Antiresorptive Therapy.

Mohammad Hadi Samadi, Pegah Sahafi, Ali Emadi Toghabeh, Hassan Kamali, Atena Aghaee• 2026• Clinical nuclear medicine

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چکیده اصلی

We report a rare case of a 40-year-old woman with longstanding craniofacial fibrous dysplasia involving the right maxilla, orbital cavity, and fronto-parietal bones. The patient underwent partial maxillary debulking 7 years ago for cosmetic reasons and orbital decompression 3 years ago, and is currently on long-term antiresorptive therapy. Bone scintigraphy with 99mTc-MDP showed multiple sites of increased osteoblastic activity. 99mTc-FAPI SPECT/CT also revealed focal uptake in craniofacial and other lesions, indicating active fibroblast proliferation. This is the first reported case of 99mTc-FAPI uptake in fibrous dysplasia, suggesting its value in evaluating fibrotic bone lesions.

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کلیدواژه‌ها

SPECT/CTbony lesionmolecular imaging

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