[Role of phytotherapeutics in diagnosis and treatment of diabetes].

چکیده اصلی

Phytotherapy relies on biologically active plant-derived compounds and preparations. The use of phytotherapeutics in treatment of diabetes consequently increases. Many plant extracts interact with key elements of glucose metabolism, e.g. through modulation of DPP-4 activity, increase in glucose intake by tissues and improvement of pancreatic beta-cells. Experimental data indicates that Hairy Rock-rose, tea plant, European olive, American ginseng, berberis or white mulberry can support glycemic control and limit the development of metabolic side effects. Despite vast literature data, the clinical efficacy of several phytotherapeutics remains ambiguous, what indicates the need to conduct further research, in particular well-designed clinical studies. Here we review plants with therapeutic potential, whose use in the treatment of diabetes has been confirmed by experimental in vitro, in vivo and clinical studies; promising directions in future studies on phytotherapeutics have also been indicated.

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